Polyploidization and Cancer

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Medicine
Polyploidization and Cancer

Polyploidization and Cancer

Name: Polyploidization and Cancer
ISBN: 9781441961983

Lauren M.F. Merlo, Li-san Wang, John W. Pepper (auth.), Randy Y. C. Poon MA, PhD (eds.)

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Limiting genome replication to once per cell cycle is vital for maintaining genome stability. Although polyploidization is of physiologically importance for several specialized cell types, inappropriate polyploidization is believed to promote aneuploidy and transformation. A growing body of evidence indicates that the surveillance mechanisms that prevent polyploidization are frequently perturbed in cancers. Progress in the past several years has unraveled some of the underlying principles that maintain genome stability. This book brings together leaders of the field to overview subjects relating to polyploidization and cancer.

Kategorien:

Medicine

Jahr:

2010

Auflage:

Verlag:

Springer-Verlag New York

Sprache:

english

Seiten:

151

ISBN 10: